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The combination of adenovirus vector, adjuvant and oral administration will unlock the potential of vector-based vaccination, with applications in Avian Influenza response, second-generation oral versions of existing vaccines, and unmet needs. The company is currently testing an avian flu vaccine in animal models and is seeking financing to initiate a clinical trial in 2009.

Advantages of the Vaxart Vaccine Platform

  • Oral delivery is strongly preferred by care providers and patients.  
  • New vaccines can be created very quickly to protect against new circulating avian flu strains, other emerging pathogens, or biodefense threats.
  • Vaxart uses efficient and standardized manufacturing methods, with essentially the same process for every Vaxart vaccine.
  • Vaxart vaccines retain potency for more than a month at room temperature, potentially allowing final distribution without refrigeration or the need for administration by trained medical staff.

  • Vaxart vaccines generate antigen-specific killer T-cell and IgA antibody responses, as well as IgG antibody responses.
  • Oral vaccination with live adenovirus (to prevent respiratory adenovirus infection) has an excellent safety record in millions of subjects.

News

October 2008: Vaxart reports demonstration of oral vaccine efficacy against lethal avian flu challenge in ferret and mouse models, at Modern Mucosal Vaccines Adjuvants & Microbicides conference in Portugal.  Read more...

June 2008: Vaxart presents at BIO International Conference in San Diego.

March 2008: Robert Fildes, former President of Biogen and CEO of Cetus, joins Vaxart Board as Chairman.  Read more...

January 2008: Vaxart profiled in Startup (Windhover publications).

November 2007: Vaxart (fka West Coast Biologicals) Completes Series A Financing. Read more...

November 2007: NAIAD division of NIH awards $600,000 SBIR grant to Vaxart to develop oral vaccine platform.

April 2006: West Coast Biologicals is a finalist in the 2006 Global Life Sciences Innovation Accelerator Competition at UCSF. 





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